Lately, there’s been a ton of buzz in the Type 1 diabetes (T1D) community about a group of medications typically used to help treat type 2 diabetes known as GLP-1 Receptor Agonists, such as Ozempic, Mounjaro, and Victoza. Did you know that those of us with T1D can greatly benefit from these medications as well? Some people with T1D are cautiously exploring taking these medications off-label and possibly even using an approach that some people refer to as “microdosing”.
This article will dive into what microdosing Ozempic means, explore why people are trying it, and discuss what the potential upsides and drawbacks might be.
Please note that this article isn’t medical advice, and these medications aren’t yet approved for the treatment of T1D. If you’re curious about any off-label use, make sure to talk with your healthcare team first!
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Taking Ozempic with Type 1 Diabetes
So, what’s the deal with these GLP-1 medications that everyone and their dog are talking about these days? Simply put, they mimic a natural hormone in our bodies that plays a big role in how we process food and feel full. They work by slowing down how quickly food leaves our stomachs, increasing feelings of fullness (adios, “food noise”), and even helping our blood sugar levels by reducing liver glucose production and decreasing insulin resistance.
For people with Type 2 Diabetes, these medications have led to better blood sugar control, significant appetite suppression, and impressive weight management results. Newer research is showing potential cardiovascular and neurodegenerative benefits, as well as aiding in substance abuse disorders.
Many people with T1D battle with weight management (hello, 5 other hormones we don’t regulate properly), can experience frustrating insulin resistance, struggle with post-meal blood sugar spikes, and sometimes feel like we’re always hungry.
This is where GLP-1s for T1D come in to save the day! These medications could offer a helping hand by improving satiety and reducing appetite, leading to easier weight management and, if necessary, weight loss. They can also help reduce insulin needs due to improved sensitivity or reduced overall food intake, and help with smoother post-meal blood sugar levels.
What is Microdosing Ozempic?
“Microdosing” in the context of Ozempic isn’t about taking a tiny amount of a psychedelic substance to boost creativity – it means using significantly lower doses of Ozempic than what’s typically prescribed for Type 2 Diabetes or weight loss. For example, the lowest therapeutic dose of Ozempic is 0.25mg. Someone who is microdosing may only take half of that dose.
The idea here is to capture some of those awesome benefits, such as improved satiety, smoother blood sugar levels, reduced food noise, and weight management, while potentially avoiding or lessening the unpleasant gastrointestinal side effects, like nausea or complete loss of appetite, that can sometimes occur with full prescribed doses.
Keep in mind that there are currently no established or medically approved “microdosing” guidelines at this time as it is a highly individualized and off-label approach.
Why I Microdose Ozempic
When I decided to try Ozempic, I was excited to experience these fantastic benefits that I had heard about firsthand. Little did I know that I was in for a rude awakening a few hours after taking the standard starting dose of 0.25 mg, when it left me feeling incredibly nauseous for several days. It was clear that a full dose wouldn’t work for me. I almost stopped taking it altogether, but decided to experiment with “microdosing”. I’ve found that taking about half of that lowest dose has been my sweet spot.
My Ozempic Results
The results have been excellent, particularly with the significant reduction in food noise, which has been incredibly liberating. My insulin requirements have decreased by approximately 20%, and I’m experiencing fewer episodes of low blood sugar and less dramatic post-meal spikes, resulting in smoother blood sugar control. Even my A1C has slightly improved.
While weight loss wasn’t my primary goal, I’ve lost about 3-5 pounds, and maintaining my current weight now feels considerably easier and less effortful. I finally feel like I can adopt a mindful eating approach, and I no longer feel the need to track macros or adhere to strict food rules constantly. I eat when I am hungry and stop eating when I feel full.
Overall, staying on track with my health goals requires much less effort. I rarely experience the late-night snack cravings that used to lead to overeating and cause blood sugar rollercoasters overnight. Plus, I no longer get “hangry,” which my family very much appreciates. I’m much better able to tolerate delayed meals without issue.
Keep in mind that these benefits aren’t solely due to the Ozempic. I’ve also been focusing on my nutrition, ensuring I eat a balanced diet with a focus on protein, fiber, and staying well-hydrated (thanks to my favorite water bottle!) Engaging in regular exercise, including daily walks and strength training at least twice a week, has also been a non-negotiable to help prevent potential muscle loss.
Talking to Your Doctor
Bringing up off-label medication use can feel a bit daunting. Open communication with your healthcare team is crucial when exploring GLP-1s with T1D. Below are a few tips:
Be Prepared
Don’t just walk in and ask for Ozempic. Do your homework! Gather information, understand the potential benefits and risks, and be ready to articulate why you’re interested and what specific struggles you’re hoping to address. Share your research, your personal challenges (like stubborn weight gain, insulin resistance, or relentless hunger), and your specific questions.
Find a Supportive Healthcare Team
This is perhaps the most crucial step. Not all endocrinologists are comfortable prescribing medications off-label, and that’s okay. You need a provider who is not only knowledgeable about T1D but also open to discussing novel approaches, even if they’re outside standard guidelines. They should be willing to listen to your concerns, weigh the potential benefits against the risks in your specific case, and collaboratively decide if this path is right for you.
If your current doctor isn’t open to the conversation, don’t be afraid to seek a second opinion from an endocrinologist who specializes in innovative T1D management or has experience with off-label prescriptions – major shout-out to Chris Szoke, The Diabetes NP, who helped me with my GLP-1 Journey!
Monitoring is Key
If your doctor agrees to explore microdosing, keeping a close eye on your blood sugars must be top of mind. This isn’t a “set it and forget it” situation. I highly recommend that you have a CGM and that you review your data and make adjustments to your treatment plan regularly.
Start Low, Go Slow
Should you and your doctor decide to proceed, the “microdosing” approach involves starting with a very low dose and titrating it up gradually as needed. This slow titration helps your body adjust, allowing you plenty of time to monitor your response, adjust your insulin needs, and manage any potential side effects. You might find that you get all of the benefits that you need with that very first low dose!
Conclusion
So, there you have it, microdosing Ozempic for Type 1 Diabetes is a complex, evolving, and off-label area that’s gaining traction among those looking for new and out-of-the-box ways to make life with diabetes just a little bit easier. It’s a testament to the constant innovation and determination within our community to find better ways to live with this condition. As women navigating the world of T1D, it’s incredibly empowering to be informed advocates for our own health. Research, ask questions, and never stop seeking the best possible care!
Remember, your safety is always the top priority, and any consideration of off-label medication use must be done under the careful guidance and supervision of a trusted healthcare professional. Your diabetes journey is unique, and finding what works best for you requires careful consideration and a true partnership with your healthcare team.
Ready to dive deeper? Check out our Ultimate Guide to Navigating GLP-1s with T1D, and if you are a woman with T1D looking to connect with others on a similar journey, make sure to join our supportive community in the Mama-Betes GLP-1 T1D Thrive Tribe Facebook Group!